Animal Lectins: A Functional View by Gerardo R. Vasta PhD, Hafiz Ahmed PhD

By Gerardo R. Vasta PhD, Hafiz Ahmed PhD

Introduces Groundbreaking techniques for Assessing Lectin Function

Lectins and their ligands are below relatively a heavy microscope as a result of their capability functions to pharmacology, immunology, melanoma remedy, and agriculture. With growing to be curiosity within the glycobiology box, the physique of study relating to lectin roles has grown at an explosive price, quite long ago two decades. Animal Lectins: A useful View presents the main updated research of those carbohydrate-binding, and almost certainly lifesaving, proteins in a single finished quantity.

This standard-setting source offers new insights into the organic roles of such a lot animal lectins, together with their functionality in an infection prevention via innate immunity. It additionally discusses such lectin behaviors as:

  • Glycoprotein folding
  • Sorting and targeting
  • Cell adhesion
  • Embryogenesis
  • Cell-cell interactions and signaling

Describes the Structural foundation of Protein-Carbohydrate Interactions

Under the editorial information of 2 major protein chemistry specialists and with contributions from well-recognized box gurus, this e-book logically and systematically discusses either intracellular and extracellular lectin features. it truly is a necessary springboard for destiny box study and a transparent and concise wisdom base that glycobiology, biochemistry, and immunology researchers can't have the funds for to be without.

Show description

Read Online or Download Animal Lectins: A Functional View PDF

Best developmental biology books

International Review of Cytology, Volume 176: A Survey of Cell Biology (International Review of Cell and Molecular Biology)

Overseas evaluate of Cytology provides present advances and accomplished studies in phone biology-both plant and animal. Articles deal with constitution and keep an eye on of gene expression, nucleocytoplasmic interactions, keep watch over of mobilephone improvement and differentiation, and phone transformation and progress. Authored through the various most efficient scientists within the box, each one quantity offers up to date info and instructions for destiny learn.

Dynamic Food Webs: Multispecies Assemblages, Ecosystem Development and Environmental Change (Theoretical Ecology Series)

Dynamic meals Webs demanding situations us to reconsider what elements could make sure ecological and evolutionary pathways of nutrients internet improvement. It touches upon the exciting concept that trophic interactions force styles and dynamics at diverse degrees of organic association: dynamics in species composition, dynamics in inhabitants life-history parameters and abundances, and dynamics in person progress, dimension and behaviour.

Metal Related Neurodegenerative Disease (International Review of Neurobiology)

This factor experiences the function of metals in neurodegenerative ailments; together with Parkinson’s and Huntington’s illness; stressed leg syndrome and NBIA problems; and Wilson’s ailment and manganese and calcium accumulation problems. An replace on advances in neuroimaging and pathology of steel similar disease is additionally awarded.

Extra resources for Animal Lectins: A Functional View

Sample text

1992 Lectins as blood typing reagents. In: Franz, H. ), Advances in Lectin Research, Vol. 5. Ullstein Mosby, Berlin, pp. 51–94. 8. Noguchi, H. 1903 On the multiplicity of the serum haemagglutinins of cold-blooded animals. Zentralbl. Bakteriol. Abt. l Orig. 34, 286. 9. Cantacuzene, J. 1912 Sur certains anticorps naturels observes chez Eupagurus prideauxii. R. Soc. Biol. 73, 663. 10. M. J. 1952 Neutralization of the anti-H agglutinin in eel serum by simple sugars. Nature 169, 825–826. 11. J. M. 1968 Isolation and characterization of a hemagglutinin from Limulus polyphemus.

Nature 169, 825–826. 11. J. M. 1968 Isolation and characterization of a hemagglutinin from Limulus polyphemus. J. Mol. Biol. 32, 453–465. 12. Hammarstrom, S. A. 1969 Purification and characterization of a blood-group A reactive hemagglutinin from the snail Helix pomatia and a study of its combining site. Biochemistry 8, 2696–2705. indd 8 9/1/2008 5:59:35 PM Introduction to Animal Lectins 9 13. F. R. 1971 Monosaccharides as specific precipitinogens of eel anti-human blood group H (O) antibody. Biochemistry 10, 3749–3760.

Describe the structural features of chitinases and chilectins, which may have arisen from the gene duplication events. Chilectins have lost the ability to cleave chitin due to mutations in the active site, but retain the ability to bind carbohydrates. REFERENCES 1. H. 1988 Bifunctional properties of lectins: Lectins redefined. Trends Biochem. Sci. 13, 480–482. 2. L. 1899 Recherches experimentales sur une agglutinine produite par la glande de l’albumen chez l’Helix pomatia. R. Acad. Sci. 129, 233.

Download PDF sample

Rated 4.70 of 5 – based on 17 votes